Product Name	IL26
Chinese Name	白介素26抗体
Alias	AK155; IL 26; IL-26; IL26_HUMAN; Interleukin 26; Interleukin-26; Protein AK155.
literatures	Specific References  (1)     |     SL2626R has been referenced in 1 publications. [IF=4.86] Ohnuma et al. Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes. (2015) J.Immuno. 194:3697-712  IHC ;  Mouse.   PubMed:25786689
Research Area	immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Dog, Pig, Cow, )
Applications	WB=1:500-2000 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	18kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IL-26: 21-120/171
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq] Function: May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. Subunit: Homodimer. Subcellular Location: Secreted. Tissue Specificity: Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level). Similarity: Belongs to the IL-10 family. SWISS: Q9NPH9 Gene ID: 55801 Database links: Entrez Gene: 55801 Human Omim: 605679 Human SwissProt: Q9NPH9 Human Unigene: 272350 Human IL-26作为炎性cell factor,可通过多重效应参与炎症过程。

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