Product Name	IL-20R alpha
Chinese Name	白介素20受体α链抗体
Alias	IL-20Rα; Interleukin-20 receptor alpha chain precursor;IL-20RA; IL20 RA; IL-20 RA; E230031K19; FLJ40993; IL-20R1; IL20RA; ZCYTOR7;Interleukin-20 receptor subunit alpha; IL-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; Cytokine receptor family 2 member 8; CRF2-8; Cytokine receptor class-II member 8; I20RA_HUMAN.
literatures	Specific References  (2)     |     SL2619R has been referenced in 2 publications. [IF=6.183] Madouri F et al. Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae.(2018) EBioMedicine. Oct 22.  IHC ;  Mouse.   PubMed:30361066 [IF=5.076] Liu Shengpeng. et al. IL-20R Activation via rIL-19 Enhances Hematoma Resolution through the IL-20R1/ERK/Nrf2 Pathway in an Experimental GMH Rat Pup Model. Oxid Med Cell Longev. 2021;2021:5913424  WB,IF ;  Rat.   PubMed:33532035
Research Area	Cell biology  immunology  The cell membrane受体  Cell Surface Molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	59kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IL-20RA: 121-220/553 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). This gene and IL20B are highly expressed in skin. The expression of both genes is found to be upregulated in Psoriasis. [provided by RefSeq] Function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26. Subunit: Heterodimer with IL20RB and heterodimer with IL10RB. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin. Similarity: Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains. SWISS: Q9UHF4 Gene ID: 53832 Database links: Entrez Gene: 53832 Human Entrez Gene: 237313 Mouse Omim: 605620 Human SwissProt: Q9UHF4 Human SwissProt: Q6PHB0 Mouse Unigene: 445868 Human Unigene: 234667 Mouse
Product Picture	Sample: Lane 1: Mouse Skin tissue lysates Lane 2: Mouse Kidney tissue lysates Lane 3: Mouse Testis tissue lysates Primary: Anti-IL-20R alpha (SL2619R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 59 kDa Observed band size: 59 kDa

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