Product Name	IL17E
Chinese Name	白介素-17E/白介素25抗体
Alias	IL-25; Interleukin-17E; IL 17E; IL-17E; IL 25; IL25; Interleukin 17E; Interleukin 25; Interleukin17E; Interleukin25; IL25_HUMAN; interleukin-25 isoform 1 precursor; interleukin-25.
literatures	Specific References  (2)     |     SL2613R has been referenced in 2 publications. [IF=3.61] Al-Samadi, Ahmed, et al. "Distinctive expression pattern of interleukin-17 cytokine family members in colorectal cancer." Tumor Biology (2015): 1-7.  IHC-P ;  Human.   PubMed:26304506 [IF=1.51] Pishdadian et al. Lung-derived innate cytokines: new epigenetic targets of allergen-specific sublingual immunotherapy. (2016) Iran.J.Basic.Med.Sci. 19:64-71  WB ;  Mouse.   PubMed:27096066
Research Area	immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	17kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IL-17E: 75-177/177
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq]. Function: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses. Subcellular Location: Secreted. Tissue Specificity: Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea. Similarity: Belongs to the IL-17 family. SWISS: Q9H293 Gene ID: 64806 Database links: Entrez Gene: 64806 Human Entrez Gene: 140806 Mouse Omim: 605658 Human SwissProt: Q9H293 Human Unigene: 302036 Human Unigene: 90154 Mouse
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (IL17E) Polyclonal Antibody, Unconjugated (SL2613R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.

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