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Product Name IL17RB Chinese Name 白介素-17B受体抗体 Alias IL17B Receptor; Interleukin-17 receptor B; IL17RB; IL-17RB; CRL 4; CRL4; Cytokine receptor CRL4; EVI 27; EVI27; IL 17 receptor B; IL 17 receptor homolog 1; IL 17B receptor; IL 17RB; IL 17Rh1; IL17BR; IL17RH1; Interleukin 17 receptor B; Interleukin 17 receptor homolog 1; Interleukin 17 receptor homolog; Interleukin 17B receptor; ecotropic viral integration site 27; interleukin-17 receptor B precursor; MGC5245; I17RB_MOUSE. literatures Specific References (3) | SL2610R has been referenced in 3 publications.[IF=8.38] Gregory, Lisa G., et al. "IL-25 drives remodelling in allergic airways disease induced by house dust mite." Thorax 68.1 (2013): 82-90. IHC-P ; Mouse.[IF=3.636] Kawamura Teruhiko. et al. Identification of genes associated with endometrial cell ageing. Mol Hum Reprod. 2021 Feb;27(2): IHC ; Human.[IF=1.813] Xie Dong-ping. et al. Effect of Electroacupuncture at Zusanli (ST36) on Sepsis Induced by Cecal Ligation Puncture and Its Relevance to Spleen. Evid-Based Compl Alt. 2020;2020:1914031 FC ; Rat.Research Area immunology The cell membrane受体 Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, Rat, Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 54kDa Cellular localization The cell membrane Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IL-17RB: 351-450/502 <Cytoplasmic> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq].
Function:
Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
Subunit:
Interacts with DAZAP2.
Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.
Tissue Specificity:
Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.
Similarity:
Contains 1 SEFIR domain.
SWISS:
Q9NRM6
Gene ID:
55540
Database links:Entrez Gene: 55540 Human
Omim: 605458 Human
SwissProt: Q9NRM6 Human
Unigene: 5470 Human
Product Picture Sample:
Lane 1: Rat Uterus tissue lysates
Lane 2: Mouse Uterus tissue lysates
Lane 3: Human A549 cell lysates
Lane 4: Human HepG2 cell lysates
Lane 5: Human HeLa cell lysates
Lane 6: Human MCF-7 cell lysates
Primary: Anti-IL17RB (SL2610R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 50 kDa
Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti-IL17RB (SL2610R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD
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