Product Name	IL-17B
Chinese Name	白介素-17B抗体
Alias	Interleukin-17B; IL17B; IL-17B; IL-20; MGC138900; MGC138901; ZCYTO7; interleukin 20; cytokine-like protein ZCYTO7; neuronal interleukin-17 related factor; interleukin-17 beta; interleukin-20; cytokine Zcyto7; neuronal interleukin-17-related factor; interleukin-17B; IL17B_MOUSE.
literatures	Specific References  (3)     |     SL2609R has been referenced in 3 publications. [IF=6.304] Yuge Gao. et al. Single cell transcriptional zonation of human psoriasis skin identifies an alternative immunoregulatory axis conducted by skin resident cells. Cell Death Dis. 2021 May;12(5):1-13  IF,IHC ;  Human.   PubMed:33958582 [IF=4.72] Aupperlee, Mark D., et al. "Epidermal growth factor receptor (EGFR)-signaling is a key mediator of hormone-induced leukocyte infiltration in the pubertal female mammary gland." Endocrinology (2014).  IHC-P ;  Mouse.   PubMed:24693965 [IF=2.885] Sun, Xinxin. et al. 0.1% Nano-silver mediates PD-1/PD-L1 pathway and alleviates chronic apical periodontitis in rats. ODONTOLOGY. 2022 Sep;:1-11  IHC ;  Rat.   PubMed:36057921
Research Area	immunology  cell factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	18kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse IL-17B: 21-120/180
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. [provided by RefSeq, Jul 2008] Function: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. Subcellular Location: Secreted. Similarity: Belongs to the IL-17 family. SWISS: Q9QXT6 Gene ID: 27190 Database links: Entrez Gene: 27190 Human Entrez Gene: 56069 Mouse Entrez Gene: 116472 Rat Omim: 604627 Human SwissProt: Q9UHF5 Human SwissProt: Q9QXT6 Mouse Unigene: 156979 Human Unigene: 59313 Mouse
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Human stomach); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (IL-17B) Polyclonal Antibody, Unconjugated (SL2609R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining. Paraformaldehyde-fixed, paraffin embedded (Rat spinal cord); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (IL-17B) Polyclonal Antibody, Unconjugated (SL2609R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.

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