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Product Name HOXB13 Chinese Name 同源盒蛋白HOXB13抗体 Alias Homeo box B13; Homeobox B13; Homeobox protein Hox B13; Homeobox protein Hox-B13; Homeobox protein HoxB13; HOX B13; HOXB 13; HOXB13; HXB13_HUMAN; PSGD; PSGD protein. Research Area Tumour Cell biology immunology Chromatin and nuclear signals Signal transduction Growth factors and hormones transcriptional regulatory factor TumourCell biologyMaker Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 31kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PSGD: 201-284/284 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008].
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain.
SWISS:
Q92826
Gene ID:
10481
Database links:Entrez Gene: 10481 Human
Entrez Gene: 15408 Mouse
Omim: 604607 Human
SwissProt: Q92826 Human
SwissProt: P70321 Mouse
Unigene: 66731 Human
Unigene: 57221 Mouse
HOXB13存在于很多哺乳动物的内分泌腺,但在人的前列腺癌及乳腺癌中表达量较高。
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