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Product Name CXCL15 Chinese Name ChemokineCXCL15抗体 Alias Lungkine; C-X-C motif chemokine 15; C-X-C motif chemokine 15; Small-inducible cytokine B15; Lungkine; small inducible cytokine subfamily B, member 15; Cxcl15; lungkine; Scyb15; weche. literatures Specific References (1) | SL2554R has been referenced in 1 publications.[IF=9.995] Bingyuan Yang. et al. Macrophages and neutrophils are necessary for ER stress-induced β cell loss. CELL REP. 2022 Aug;40:111255 IF ; Mouse.Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Mouse, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 18kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse CXCL15: 68-167/167 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail CXCL15 (Lungkine) is a CXC chemokine that is expressed in murine lung epithelial cells and, to a lesser extent, in certain fetal tissues. No human homolog has been identified and a specific cell surface receptor has not yet been found. Lungkine expression in lung tissue is elevated in response to inflammation, at which time it acts to specifically recruit neutrophils and direct them into the lung airway.
Function:
Chemotactic for neutrophils. May be involved in lung-specific neutrophil trafficking during normal and inflammatory conditions.
Subcellular Location:
Secreted.
Tissue Specificity:
Expression restricted to the lung, produced by bronchoepithelial cells and is released into the airways. Expressed at low levels in fetal lung.
Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.
SWISS:
Q9WVL7
Gene ID:
20309
Database links:Entrez Gene: 20309 Mouse
SwissProt: Q9WVL7 Mouse
Unigene: 64326 Mouse
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