Product Name	ALT1
Chinese Name	谷丙氨酸氨基转移酶1抗体
Alias	Alanine aminotransferase; AAT 1; AAT1; Alanine aminotransferase 1; alanine aminotransferase; ALT 1; ALT1; Glutamic alanine transaminase 1; Glutamic pyruvate transaminase; Glutamic pyruvic transaminase 1; Glutamic-alanine transaminase; GPT 1; GPT; GPT1; SGPT; ALAT1_HUMAN.
Research Area	Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Pig, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	55kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ALT1: 301-400/496
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Alanine Transaminase [glutamic pyruvate transaminase - GPT] participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. Pyridoxal phosphate is a known cofactor. Expression is induced by glucocorticoids. This enzyme is present in a high concentration in liver tissue and it's release into the blood indicates liver disease or damage. Function: Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. Subcellular Location: Cytoplasm. Tissue Specificity: Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue. Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily. SWISS: P24298 Gene ID: 2875 Database links: Entrez Gene: 539188 Cow Entrez Gene: 2875 Human Entrez Gene: 76282 Mouse Entrez Gene: 81670 Rat Omim: 138200 Human SwissProt: A4IFH5 Cow SwissProt: P24298 Human SwissProt: Q8QZR5 Mouse SwissProt: P25409 Rat Unigene: 103502 Human Unigene: 30130 Mouse Unigene: 6318 Rat
Product Picture	Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-ALT1 (SL2532R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD

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