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Rabbit Anti-CD94 antibody
Rabbit Anti-CD94 antibody
Killer cell lectin-like receptor subfamily D member 1; CD 94; CD94 antigen; KLRD 1; KLRD1; KLRD1 protein; KP 43; KP43; Natural killer cells antigen CD94; NK cell receptor; Killer cell lectin-like receptor subfamily D member 1; KLRD1_HUMAN.
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Product Name CD94
Chinese Name NK细胞表面抑制性受体CD94抗体
Alias Killer cell lectin-like receptor subfamily D member 1; CD 94; CD94 antigen; KLRD 1; KLRD1; KLRD1 protein; KP 43; KP43; Natural killer cells antigen CD94; NK cell receptor; Killer cell lectin-like receptor subfamily D member 1; KLRD1_HUMAN.  
Research Area immunology  The cell membrane受体  Cell type markers  Natural killer cells  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Rat, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 20kDa
Detection molecular weight 43 kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CD94: 71-179/179 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]

Function:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Subunit:
Can form disulfide-bonded heterodimer with NKG2 family members.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Natural killer cells.

Similarity:
Contains 1 C-type lectin domain.

SWISS:
Q13241

Gene ID:
3824

Database links:

Entrez Gene: 3824 Human

Omim: 602894 Human

SwissProt: Q13241 Human

Unigene: 524251 Human

Unigene: 562457 Human



Product Picture
Sample:
Lymph node (Mouse) Lysate at 40 ug
Primary: Anti-CD94 (SL2521R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kD
Observed band size: 20 kD

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