Product Name	CEBP-alpha
Chinese Name	transcriptional regulatory factorC/EBP α 抗体
Alias	Apoptotic cysteine protease; Apoptotic protease Mch 5; C/EBP alpha; CAP4; Caspase 8 precursor; CCAAT Enhancer Binding Protein alpha; CEBP; CEBP A; CEBP alpha; CEBPA; FADD homologous ICE/CED 3 like protease; FADD like ICE; FLICE; ICE like apoptotic protease 5; ICE8; MACH; MCH5; MORT1 associated CED 3 homolog;
literatures	Specific References  (2)     |     SL24540R has been referenced in 2 publications. [IF=3.553] Man Luo. et al. miR136 regulates proliferation and differentiation of small tail han sheep preadipocytes. ADIPOCYTE. 2023;12(1):Article: 2173966  WB ;  Sheep,Human.   PubMed:36722834 [IF=3.231] Zhen Zhou. et al. Myogenic Determination and Differentiation of Chicken Bone Marrow-Derived Mesenchymal Stem Cells under Different Inductive Agents. ANIMALS. 2022 Jan;12(12):1531  WB ;  Chicken.   PubMed:35739868
Research Area	Tumour  Cardiovascular  Chromatin and nuclear signals  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	39kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CEBP-alpha: 251-350/358
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. [provided by RefSeq, Jul 2008]. Function: C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Subunit: Interacts with PRDM16. Binds DNA as a dimer and can form stable heterodimers with C/EBP beta and gamma. Interacts with UBN1. Interacts with HBV protein X. Interacts with ZNF638; this interaction increases transcriptional activation. Subcellular Location: Nucleus Similarity: Belongs to the bZIP family. C/EBP subfamily. Contains 1 bZIP domain. SWISS: P49715 Gene ID: 1050 Database links: Entrez Gene: 1050 Human Entrez Gene: 12606 Mouse Entrez Gene: 24252 Rat Omim: 116897 Human SwissProt: P49715 Human SwissProt: P53566 Mouse SwissProt: P05554 Rat Unigene: 76171 Human Unigene: 349667 Mouse Unigene: 153603 Rat Unigene: 204833 Rat
Product Picture	Sample: Lane 1: Stomach (Mouse) Lysate at 40 ug Lane 2: Pancreas (Mouse) Lysate at 40 ug Lane 3: Lung (Mouse) Lysate at 40 ug Lane 4: Heart (Mouse) Lysate at 40 ug Lane 5: Liver (Rat) Lysate at 40 ug Lane 6: Heart (Rat) Lysate at 40 ug Primary: Anti-CEBP-alpha (SL24540R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 46 kD

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