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Product Name CCL1 precursor Chinese Name 嗜酸粒细胞趋化蛋白CCL1前体蛋白抗体 Alias I-309; TCA3; C-C motif chemokine 1 precursor; chemokine (C-C motif) ligand 1; BF534335; Scya1; Chemokine CC Motif Ligand 1; inflammatory cytokine I-309; P500; SCYA1; SISe; small inducible cytokine A1; Ccl1; Small-inducible cytokine A1; T lymphocyte secreted protein I-309; CCL1_HUMAN. Research Area Cell biology immunology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Rabbit, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 10kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human C-C motif chemokine 1 precursor: 21-30/96 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq, Jul 2008].
Function:
Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.
Subunit:
Monomer.
Subcellular Location:
Secreted.
Similarity:
Belongs to the intercrine beta (chemokine CC) family.
SWISS:
P22362
Gene ID:
6346
Database links:Entrez Gene: 6346 Human
Omim: 182281 Human
SwissProt: P22362 Human
Unigene: 72918 Human
CCL1属于CCChemokine家族,是由活化的T细胞分泌的glycoprotein。CCL1是一小分子的cell factorC与细胞表面的Chemokine受体CCR8结合,对单核细胞,Natural killer cells,未成熟的B细胞和树突状细胞有细胞趋化作用.
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