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Product Name IFNB1 Chinese Name Interferonβ抗体 Alias Interferon beta; Fibroblast interferon; IFB; IFF; IFN beta; IFN-Beta; IFNB 1; IFNB; Interferon beta 1 fibroblast; Interferon beta precursor; IFNB_HUMAN; IFNB_MOUSE. literatures Specific References (3) | SL23733R has been referenced in 3 publications.[IF=6.107] Nan Zang. et al. cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease. ISCIENCE. 2022 Sep;:105145 WB ; Mouse.[IF=5.191] Huiqing Hu. et al. cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress. Faseb J. 2022 May;36(5):e22266 WB ; Mouse.[IF=3.871] H.Q. Hu. et al. The STING-IRF3 pathway is involved in lipotoxic injury of pancreatic β cells in type 2 diabetes. Mol Cell Endocrinol. 2020 Dec;518:110890 WB ; Mouse.Research Area Tumour Cell biology immunology Interferon Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Mouse, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 20kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse IFNB1: 22-100/184 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC Ⅰ molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.
Function:
Has antiviral, antibacterial and anticancer activities.
Subunit:
Monomer.
Subcellular Location:
Secreted.
Similarity:
Belongs to the alpha/beta interferon family.
SWISS:
P01575
Gene ID:
15977
Database links:Entrez Gene: 15977 Mouse
SwissProt: P01575 Mouse
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