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Rabbit Anti-IFNB1 antibody
Rabbit Anti-IFNB1 antibody
Interferon beta; Fibroblast interferon; IFB; IFF; IFN beta; IFN-Beta; IFNB 1; IFNB; Interferon beta 1 fibroblast; Interferon beta precursor; IFNB_HUMAN; IFNB_MOUSE.
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Details

Product Name IFNB1
Chinese Name Interferonβ抗体
Alias Interferon beta; Fibroblast interferon; IFB; IFF; IFN beta; IFN-Beta; IFNB 1; IFNB; Interferon beta 1 fibroblast; Interferon beta precursor; IFNB_HUMAN; IFNB_MOUSE.  
literatures
Specific References  (3)     |     SL23733R has been referenced in 3 publications.
[IF=6.107] Nan Zang. et al. cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease. ISCIENCE. 2022 Sep;:105145  WB ;  Mouse.  
[IF=5.191] Huiqing Hu. et al. cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress. Faseb J. 2022 May;36(5):e22266  WB ;  Mouse.  
[IF=3.871] H.Q. Hu. et al. The STING-IRF3 pathway is involved in lipotoxic injury of pancreatic β cells in type 2 diabetes. Mol Cell Endocrinol. 2020 Dec;518:110890  WB ;  Mouse.  
Research Area Tumour  Cell biology  immunology  Interferon  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Mouse, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 20kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from mouse IFNB1: 22-100/184 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC Ⅰ molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.

Function:
Has antiviral, antibacterial and anticancer activities.

Subunit:
Monomer.

Subcellular Location:
Secreted.

Similarity:
Belongs to the alpha/beta interferon family.

SWISS:
P01575

Gene ID:
15977

Database links:

Entrez Gene: 15977 Mouse

SwissProt: P01575 Mouse



Product Picture
Sample:
Lung (Rat) Lysate at 40 ug
Primary: Anti-IFN-Beta (SL23733R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kD
Observed band size: 32 kD

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