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Product Name PDLIM1 Chinese Name Cytoskeleton蛋白C端PDLIM1抗体 Alias C terminal LIM domain protein 1; C-terminal LIM domain protein 1; Carboxy terminal LIM domain protein 1; CLIM 1; CLIM1; CLP 36; CLP36; Elfin; Enigma; Enigma homolog; hCLIM 1; hCLIM1; LIM domain protein CLP 36; LIM domain protein CLP-36; LIM domain protein CLP36; PDLI1_HUMAN; PDLIM 1; Pdlim1; PDZ and LIM domain 1; PDZ and LIM domain protein 1. Research Area Tumour Cell biology immunology Chromatin and nuclear signals The new supersedes the old Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 36kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PDLIM1: 251-329/329 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail PDLIM1 is a cytoskeletal protein that may act as an adapter that brings other proteins to the cytoskeleton. PDLIM1 is strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung, and minimally expressed in liver, thymus, kidney, prostate and pancreas.
It is not found in the brain, testis, ovary, and peripheral blood leukocytes.
Function:
Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton.
Subunit:
Interacts with alpha-actinins 1, 2 and 4.
Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. Note=Associates with the actin stress fibers.
Tissue Specificity:
Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes.
Similarity:
Contains 1 LIM zinc-binding domain.
Contains 1 PDZ (DHR) domain.
SWISS:
O00151
Gene ID:
9124
Database links:Entrez Gene: 9124 Human
Entrez Gene: 54132 Mouse
Omim: 605900 Human
SwissProt: O00151 Human
SwissProt: O70400 Mouse
SwissProt: Q3TZ17 Mouse
Unigene: 368525 Human
Unigene: 5567 Mouse
Unigene: 11170 Rat
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