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Rabbit Anti-GAS2L3 antibody
Rabbit Anti-GAS2L3 antibody
GAS2 like protein 3; Gas2l3; Gm240; Growth arrest specific 2 like 3; Growth arrest specific protein 2 like 3; GA2L3_HUMAN.
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  • NO.:SL23297R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Dog,Rabbit,)
    Applications:IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name GAS2L3
Chinese Name 生长停滞特异性蛋白2家族3抗体
Alias GAS2 like protein 3; Gas2l3; Gm240; Growth arrest specific 2 like 3; Growth arrest specific protein 2 like 3; GA2L3_HUMAN.  
literatures
Specific References  (1)     |     SL23297R has been referenced in 1 publications.
[IF=3.258] Yan Zhou. et al. Elevated GAS2L3 Expression Correlates With Poor Prognosis in Patients With Glioma: A Study Based on Bioinformatics and Immunohistochemical Analysis. Front Genet. 2021; 12: 649270  IHC ;  Human.  
Research Area Cell biology  Apoptosis  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Dog, Rabbit, )
Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 75kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GAS2L3: 251-350/694 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail GAS2L3 (Growth arrest-specific 2 like 3) a member of the GAS2 family, is similar in sequence to the mouse protein GAS2, an actin-associated protein expressed at high levels in growth-arrested cells. The specific function of this protein is unknown.

Function:
Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network.

Subunit:
Interacts (via CH domain) with F-actin. Interacts (via C terminus) with microtubules.

Subcellular Location:
Cytoplasm

Tissue Specificity:
Expressed in the pancreas, heart, liver, placenta, brain, skeletal muscle, kidney and lung.

Similarity:
Belongs to the GAS2 family.
Contains 1 CH (calponin-homology) domain.
Contains 1 GAR domain.

SWISS:
Q86XJ1

Gene ID:
283431

Database links:

Entrez Gene: 283431 Human

SwissProt: Q86XJ1 Human

Unigene: 20575 Human



Product Picture
Paraformaldehyde-fixed, paraffin embedded (Rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GAS2L3) Polyclonal Antibody, Unconjugated (SL23297R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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