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Product Name GAS2L3 Chinese Name 生长停滞特异性蛋白2家族3抗体 Alias GAS2 like protein 3; Gas2l3; Gm240; Growth arrest specific 2 like 3; Growth arrest specific protein 2 like 3; GA2L3_HUMAN. literatures Specific References (1) | SL23297R has been referenced in 1 publications.[IF=3.258] Yan Zhou. et al. Elevated GAS2L3 Expression Correlates With Poor Prognosis in Patients With Glioma: A Study Based on Bioinformatics and Immunohistochemical Analysis. Front Genet. 2021; 12: 649270 IHC ; Human.Research Area Cell biology Apoptosis Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Dog, Rabbit, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 75kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GAS2L3: 251-350/694 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail GAS2L3 (Growth arrest-specific 2 like 3) a member of the GAS2 family, is similar in sequence to the mouse protein GAS2, an actin-associated protein expressed at high levels in growth-arrested cells. The specific function of this protein is unknown.
Function:
Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network.
Subunit:
Interacts (via CH domain) with F-actin. Interacts (via C terminus) with microtubules.
Subcellular Location:
Cytoplasm
Tissue Specificity:
Expressed in the pancreas, heart, liver, placenta, brain, skeletal muscle, kidney and lung.
Similarity:
Belongs to the GAS2 family.
Contains 1 CH (calponin-homology) domain.
Contains 1 GAR domain.
SWISS:
Q86XJ1
Gene ID:
283431
Database links:Entrez Gene: 283431 Human
SwissProt: Q86XJ1 Human
Unigene: 20575 Human
Product Picture Paraformaldehyde-fixed, paraffin embedded (Rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GAS2L3) Polyclonal Antibody, Unconjugated (SL23297R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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