Product Name	CXCL10/IP10
Chinese Name	CXCL10Chemokine10/Interferon诱导蛋白10抗体
Alias	10 kDa interferon gamma induced protein; C7; Chemokine (C X C motif) ligand 10; Chemokine CXC motif ligand 10; Crg 2; CRG2; CXCL 10; CXCL10; Gamma IP10; gIP 10; GIP10; IFI 10; IFI10; INP 10; INP10; Interferon activated gene 10; Interferon gamma induced cell line; Interferon inducible cytokine IP 10; MOB1; SCYB 10; SCYB10; Small inducible cytokine B10; Small inducible cytokine B10 precursor; Small inducible cytokine subfamily B (Cys X Cys) member 10; Gamma-IP-10.
literatures	Specific References  (1)     |     SL23238R has been referenced in 1 publications. [IF=4.493] Fan Jiahui. et al. Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis. J IMMUNOL RES. 2022;2022:2932837  IHC ;  Human.   PubMed:35785034
Research Area	Tumour  Cell biology  immunology  Growth factors and hormones  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	10kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CXCL10/IP10: 29-70/98
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020] Function: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Subcellular Location: Secreted. Post-translational modifications: CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes. Similarity: Belongs to the intercrine alpha (chemokine CxC) family. SWISS: P02778 Gene ID: 3627 Database links: Entrez Gene: 3627 Human Entrez Gene: 15945 Mouse Entrez Gene: 245920 Rat Omim: 147310 Human SwissProt: P02778 Human SwissProt: P17515 Mouse SwissProt: P48973 Rat Unigene: 632586 Human Unigene: 877 Mouse Unigene: 10584 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Human liver cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CXCL10) Polyclonal Antibody, Unconjugated (SL23238R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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