Product Name	Nucleobindin 2
Chinese Name	新的饱食分子蛋白抗体
Alias	DNA binding protein NEFA; DNA-binding protein NEFA; Gastric cancer antigen Zg4; NEFA; Nucb2; NUCB2_HUMAN; Nucleobindin-2; Nucleobinding 2.
Research Area	Cardiovascular  Cell biology  immunology  Neurobiology  Growth factors and hormones  Diabetes
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	50kDa
Cellular localization	The nucleus cytoplasmic The cell membrane Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Nucleobindin 2: 251-350/420
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. This protein binds calcium and has EF-folding domains. [provided by RefSeq, Oct 2011]. Function: Calcium-binding protein. May have a role in calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. Subcellular Location: Golgi apparatus. Membrane; Peripheral membrane protein. Cytoplasm. Secreted. Endoplasmic reticulum. Nucleus envelope. Note=Golgi retention is mediated by its N-terminal region. Nesfatin-1: Secreted. Tissue Specificity: Predominantly expressed in spleen, testis and normal stomach. Similarity: Belongs to the nucleobindin family. Contains 2 EF-hand domains. SWISS: P80303 Gene ID: 4925 Database links: Entrez Gene: 4925 Human Entrez Gene: 53322 Mouse Entrez Gene: 59295 Rat Omim: 608020 Human SwissProt: P80303 Human SwissProt: P81117 Mouse SwissProt: Q9JI85 Rat Unigene: 654599 Human Unigene: 9901 Mouse Unigene: 41602 Rat
Product Picture	Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-Nucleobindin 2 (SL23044R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 50 kD Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-Nucleobindin 2 (SL23044R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50kD Observed band size: 50 kD

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