Product Name	PGK1
Chinese Name	磷酸激酶1抗体
Alias	Cell migration-inducing gene 10 protein; MGC117307; MGC8947; MIG10; pgk1; PGK1_HUMAN; PGKA; Phosphoglycerate kinase 1; Primer recognition protein 2; PRP 2; PRP 2.
Research Area	Tumour  Cell biology  immunology  Neurobiology  Signal transduction  Kinases and Phosphatases  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	44kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PGK1: 81-180/417
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. This gene lies on the X-chromosome, while a related pseudogene also has been found on the X-chromosome and another on chromosome 19. [provided by RefSeq] Function: In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). Subunit: Monomer. Subcellular Location: Cytoplasm. DISEASE: Phosphoglycerate kinase 1 deficiency (PGK1D) [MIM:300653]: A condition with a highly variable clinical phenotype that includes hemolytic anemia, rhabdomyolysis, myopathy and neurologic involvement. Patients can express one or more of these manifestations. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the phosphoglycerate kinase family. SWISS: P00558 Gene ID: 5230 Database links: Entrez Gene: 5230 Human Entrez Gene: 18655 Mouse Entrez Gene: 24644 Rat Omim: 311800 Human SwissProt: P00558 Human SwissProt: P09411 Mouse SwissProt: P16617 Rat Unigene: 78771 Human Unigene: 336204 Mouse Unigene: 336205 Mouse Unigene: 108127 Rat
Product Picture	Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti- PGK1 (SL21867R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kD Observed band size: 44 kD

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