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Product Name DNPEP Chinese Name 天冬氨酰氨基肽酶抗体 Alias Aspartyl aminopeptidase; ASPEP; DAP; DNPEP_HUMAN. Research Area Signal transduction Channel protein Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 52kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human DNPEP: 251-350/475 Lsotype IgG Purification affinity purified by Protein A Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins. [provided by RefSeq, Jul 2008]
Function:
Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism.
Subunit:
Tetrahedron-shaped homododecamer built from six homodimers.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the peptidase M18 family.
SWISS:
Q9ULA0
Gene ID:
23549
Database links:Entrez Gene: 23549 Human
Entrez Gene: 13437 Mouse
Omim: 611367 Human
SwissProt: Q9ULA0 Human
SwissProt: Q9Z2W0 Mouse
Unigene: 258551 Human
Unigene: 24680 Mouse
Unigene: 65448 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DNPEP) Polyclonal Antibody, Unconjugated (SL20423R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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