Product Name	Somatostatin Receptor 5
Chinese Name	生长抑素受体5抗体
Alias	somatostatin receptor 5; SS5R; Somatostatin receptor subtype 5; Somatostatin receptor type 5; SS 5R; SS5 R; SST R5; SSTR 5; SSTR5; SS-5-R; SS5-R; SS5R; SSR5_MOUSE.
Research Area	Tumour  The cell membrane受体  G protein-coupled receptor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Rat, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	39kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse Somatostatin Receptor 5: 1-100/362 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010] Function: Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: O08858 Gene ID: 20609 Database links: Entrez Gene: 20609 Mouse Entrez Gene: 25354 Rat SwissProt: O08858 Mouse SwissProt: P30938 Rat Unigene: 353282 Mouse Unigene: 91342 Rat SSTR5为G-蛋白偶联的The cell membrane受体,SSTR5的表达与Tumour的分布、发生和发展中起重要作用。
Product Picture	Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti- Somatostatin Receptor 5 (SL20418R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 39 kD Observed band size: 54 kD

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