TEL: +86 571 56623320 EMAIL: [email protected]
Product Name TSPAN6 Chinese Name 四分子交联体6抗体(四旋蛋白) Alias Putative NF kappa B activating protein 321; Putative NF-kappa-B-activating protein 321; T245; T245 protein; Tetraspan TM4SF; Tetraspanin 6; Tetraspanin TM4 D; Tetraspanin TM4-D; Tetraspanin TM4D; Tetraspanin-6; Tm4sf; TM4SF6; Transmembrane 4 superfamily member 6; TSN6_HUMAN; TSPAN 6; Tspan-6; TSPAN6; Tspan6 protein. Research Area Tumour Cell biology Chromatin and nuclear signals Neurobiology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Pig, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 28kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TSPAN6: 1-100/245 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Tetraspanins are a group of hydrophobic membrane proteins that interact with a wide variety of proteins including intracellular signaling molecules, integrins and membrane receptors. Members of the tetraspanin family are characterized by the presence of four hydrophobic domains and play a role in cell development, activation, growth and motility. TSPAN6 (tetraspanin-6), also known as A15 homolog, putative NF-kappa-B-activating protein 321, T245 protein, tetraspanin TM4-D or TM4SF6 (transmembrane 4 superfamily member 6), is a 245 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. TSPAN6 is expressed at high levels in brain, with lower levels of expression found in colon, lung, pancreas, prostate, retina and melanocytes, as well as fetal heart, liver and spleen. The gene encoding TSPAN6 maps to the human X chromosome.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the tetraspanin (TM4SF) family.
SWISS:
O43657
Gene ID:
7105
Database links:Entrez Gene: 7105 Human
Omim: 300191 Human
SwissProt: O43657 Human
Unigene: 43233 Human
Product Picture Paraformaldehyde-fixed, paraffin embedded (mouse heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TSPAN6) Polyclonal Antibody, Unconjugated (SL20292R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Scan Wechat Qrcode