Product Name	RTN4RL1
Chinese Name	Nogo66受体相关蛋白3抗体
Alias	DKFZp547J144; NgR 3; NgR3; NGRH 2; NGRH2; NGRL2; Nogo 66 receptor homolog 2; Nogo 66 receptor related protein 3; Nogo receptor like 2; Reticulon 4 receptor like 1; R4RL1_HUMAN.
literatures	Specific References  (2)     |     SL20071R has been referenced in 2 publications. [IF=2.515] Li T et al. Digital gene expression analyses of mammary glands from meat ewes naturally infected with clinical mastitis. R. Soc. open sci. 2019,6: 181604.  WB&IHC-P ;  Sheep.   PubMed:doi:10.1098/rsos.181604 [IF=2.515] Li T et al. Digital gene expression analyses of mammary glands from meat ewes naturally infected with clinical mastitis.R Soc Open Sci. 2019 Jul 3;6(7):181604.  WB&IHC ;  Sheep.   PubMed:31417691
Research Area	Cell biology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	45kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RTN4RL1: 101-300/441
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	NgR3 is a 441 amino acid protein that belongs to the Nogo receptor family. Localized to the cell membrane, NgR3 contains 8 LRR (leucine-rich) repeats. NgR3 is predominantly expressed in brain, where it localizes to the surface of neurons, but is also found at lower levels in lung, placenta, kidney, mammary gland, skeletal muscle, spleen and salivary gland. NgR3 is thought to play a role in the regulation of axonal regeneration and plasticity in the adult central nervous system. The gene that encodes NgR3 maps to human chromosome 17, which makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Function: RTN4RL1 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Note: Localized to the surface of neurons, including axons Tissue Specificity: Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen. Similarity: Belongs to the Nogo receptor family. Contains 8 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. SWISS: Q86UN2 Gene ID: 146760 Database links: Entrez Gene: 146760 Human Entrez Gene: 237847 Mouse Entrez Gene: 303311 Rat Omim: 610461 Human SwissProt: Q86UN2 Human SwissProt: Q8K0S5 Mouse SwissProt: Q80WD0 Rat Unigene: Human

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