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Rabbit Anti-DPCR1 antibody
Rabbit Anti-DPCR1 antibody
bCX105N19.6; Diffuse panbronchiolitis critical region 1; Diffuse panbronchiolitis critical region; Diffuse panbronchiolitis critical region protein 1; DKFZp666O235; DPCR protein; DPCR1; DPCR1_HUMAN; MGC126710; MGC126712; OTTHUMP00000062447; PBLT.
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Details

Product Name DPCR1
Chinese Name 弥漫性泛细支气管炎相关蛋白1抗体
Alias bCX105N19.6; Diffuse panbronchiolitis critical region 1; Diffuse panbronchiolitis critical region; Diffuse panbronchiolitis critical region protein 1; DKFZp666O235; DPCR protein; DPCR1; DPCR1_HUMAN; MGC126710; MGC126712; OTTHUMP00000062447; PBLT.  
Research Area Tumour  Cell biology  immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Rat, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 51kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from mouse DPCR1: 51-150/517 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail DPCR1 is a 517 amino acid single-pass type I membrane protein that exists as 2 alternatively spliced isoforms. Expressed in adult small intestine, uterus, esophagus, lung, kidney, testis, rectum, stomach, cervix and skin, DPCR1 has also been observed in fetal kidney, lung and heart. The gene encoding DPCR1 maps to a region on chromosome 6 that is shared by seven other genes, which have been linked to diffuse panbronchiolitis. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Function:
Detected in lung, esophagus, stomach, rectum, skin, cervix, testis, kidney, uterus and small intestine.

Subcellular Location:
Membrane.

Tissue Specificity:
Expressed in fetal heart, kidney and lung.

SWISS:
Q3MIW9

Gene ID:
135656

Database links:

Entrez Gene: 135656 Human

Omim: 613928 Human

SwissProt: Q3MIW9 Human

Unigene: 631993 Human



Product Picture
Sample:
Pancreas (Mouse) Lysate at 40 ug
Primary: Anti- DPCR1 (SL20005R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD

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