Product Name	ACTR1B
Chinese Name	肌动蛋白相关蛋白1B抗体
Alias	Actin related protein 1B; Actin-related protein 1B; ACTR 1B; ACTY_HUMAN; ARP 1B; ARP1 actin related protein 1 homolog B; ARP1 actin related protein 1 homolog B centractin beta (yeast); ARP1 actin related protein 1 homolog B centractin beta; ARP1 actin related protein 1 yeast homolog B centractin beta; ARP1 yeast homolog B; ARP1B; Beta centractin; Beta-centractin; Centractin beta (Yeast); Centractin beta; CTRN 2; CTRN2; PC 3; PC3.
Research Area	Cell biology  Signal transduction  Binding protein  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	42kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ARP1B: 301-376/376
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008] Function: Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. Subcellular Location: Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Similarity: Belongs to the actin family. ARP1 subfamily. SWISS: P42025 Gene ID: 10120 Database links: Entrez Gene: 100125305 Cow Entrez Gene: 611680 Dog Entrez Gene: 10120 Human Entrez Gene: 226977 Mouse Entrez Gene: 316333 Rat Omim: 605144 Human SwissProt: A4IFE3 Cow SwissProt: P42025 Human SwissProt: Q8R5C5 Mouse Unigene: 98791 Human Unigene: 28521 Mouse
Product Picture	Sample: Molt-4(Human) Cell Lysate at 30 ug HepG2(Human) Cell Lysate at 30 ug Primary: Anti-PC3 (SL19902R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD

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