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Product Name RHBG Chinese Name RH家族B型glycoproteinRHBG抗体 Alias Ammonium transporter Rh type B; Rh family type B glycoprotein; Rh type B glycoprotein; RHBG; RHBG_HUMAN; Rhesus blood group family type B glycoprotein; SLC42A2. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Cow, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 47kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RHBG: 331-430/441 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes one of two non-erythroid members of the Rhesus (Rh) protein family. Non-erythroid Rh protein family members are mainly expressed in the kidney and belong to the methylammonium-ammonium permease/ammonia transporters superfamily. All Rh family proteins are predicted to be transmembrane proteins with 12 membrane spanning domains and intracytoplasmic N- and C-termini. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Function:
Functions as a specific ammonium transporter.
Subunit:
Interacts (via C-terminus) with ANK2 and ANK3; required for targeting to the basolateral membrane.
Subcellular Location:
Basolateral cell membrane. Cytoplasmic vesicle membrane.
Tissue Specificity:
Specifically expressed in kidney. Also detected in liver and ovary.
Post-translational modifications:
N-glycosylated.
DISEASE:
Fetally expressed by kidney and to a lower extent in liver.
Similarity:
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
SWISS:
Q9H310
Gene ID:
57127
Database links:Entrez Gene: 57127 Human
Omim: 607079 Human
SwissProt: Q9H310 Human
Unigene: 131835 Human
Product Picture Sample: Kidney (Mouse) Lysate at 40 ug
Primary: Anti-RHBG (SL19868R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 49 kD
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