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Product Name SLC39A2 Chinese Name 溶质载体家族蛋白39成员A2抗体 Alias 6A1; Eti-1; Eti1; hZIP2; MGC119190; OTTHUMP00000164402; S39A2_HUMAN; SLC39A2; Solute carrier family 39 (zinc transporter) member 2; Solute carrier family 39 member 2; Zinc transporter ZIP2; ZIP 2; ZIP-2; ZIP2; Zrt and Irt like protein 2; Zrt- and Irt-like protein 2. Research Area Tumour Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 33kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC39A2: 31-130/309 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the ZIP family of metal ion transporters. The encoded protein functions as a zinc transporter. Mutations in this gene may be associated with susceptibility to carotid artery disease. Multiple transcript variants have been described. [provided by RefSeq, Mar 2010]
Function:
Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Expressed only in prostate and uterine epithelial cells.
Similarity:
Belongs to the ZIP transporter (TC 2.A.5) family.
SWISS:
Q9NP94
Gene ID:
29986
Database links:Entrez Gene: 29986 Human
Entrez Gene: 214922 Mouse
Omim: 612166 Human
SwissProt: Q9NP94 Human
SwissProt: Q2HIZ9 Mouse
Unigene: 175783 Human
Unigene: 281343 Mouse
Unigene: 51972 Rat
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