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Product Name SLC25A3 Chinese Name 溶质载体家族蛋白25成员A3抗体 Alias mitochondrial; Mitochondrial phosphate carrier protein; MPCP_HUMAN; OK/SW cl.48; PHC; Phosphate carrier protein; Phosphate carrier protein mitochondrial; Phosphate carrier protein mitochondrial precursor; Phosphate transport protein; PTP; Slc25a3; Solute carrier family 25 member 3; Solute carrier family 25 mitochondrial carrier phosphate carrier member 3. Research Area Tumour Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 35kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC25A3: 51-150/362 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene catalyzes the transport of phosphate into the mitochondrial matrix, either by proton cotransport or in exchange for hydroxyl ions. The protein contains three related segments arranged in tandem which are related to those found in other characterized members of the mitochondrial carrier family. Both the N-terminal and C-terminal regions of this protein protrude toward the cytosol. Multiple alternatively spliced transcript variants have been isolated. [provided by RefSeq, Jul 2008]
Function:
Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+).
Subunit:
Interacts with PPIF; the interaction is impaired by CsA.
Subcellular Location:
Mitochondrion inner membrane.
DISEASE:
Mitochondrial phosphate carrier deficiency (MPCD)
Similarity:
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.
SWISS:
Q00325
Gene ID:
5250
Database links:Entrez Gene: 5250 Human
Omim: 600370 Human
SwissProt: Q00325 Human
Unigene: 290404 Human
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