Product Name	RBPMS
Chinese Name	RBPMS蛋白抗体
Alias	FLJ32971; Heart and RRM expressed sequence; Hermes; RBP MS; RBP-MS; Rbpms; RBPMS_HUMAN; RNA binding protein gene with multiple splicing; RNA-binding protein with multiple splicing.
Research Area	Cell biology  Binding protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	22kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RBPMS: 1-100/196
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] Function: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA. Subcellular Location: Nucleus. Cytoplasm. Tissue Specificity: Ubiquitously expressed, at various levels depending on the isoform and the tissue. Similarity: Contains 1 RRM (RNA recognition motif) domain. SWISS: Q93062 Gene ID: 11030 Database links: Entrez Gene: 428738 Chicken Entrez Gene: 614417 Cow Entrez Gene: 11030 Human Entrez Gene: 19663 Mouse Entrez Gene: 498642 Rat Omim: 601558 Human SwissProt: Q9W6I1 Chicken SwissProt: Q93062 Human SwissProt: Q9WVB0 Mouse Unigene: 334587 Human Unigene: 323997 Mouse

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