Product Name	RBMS1/Cervical cancer oncogene 4
Chinese Name	宫颈癌癌基因4抗体
Alias	c myc gene single strand binding protein 2; C2orf12; Cervical cancer oncogene 4; HCC 4; MSSP 2; MSSP 3; MSSP; MSSP-1; MSSP-2; MSSP-3; MSSP1; RBMS1; RBMS1_HUMAN; RNA binding motif, single stranded interacting protein 1; RNA-binding motif; SCR2; Single stranded DNA binding protein MSSP 1; Single-stranded DNA-binding protein MSSP-1; single-stranded-interacting protein 1; suppressor of cdc 2 (cdc13) with RNA binding motif 2; Suppressor of CDC2 with RNA binding motif 2; Suppressor of CDC2 with RNA-binding motif 2; YC1.
Research Area	Tumour  Apoptosis  Cyclin  transcriptional regulatory factor  Binding protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	45kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RBMS1/Cervical cancer oncogene 4: 181-280/406
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009] Function: Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication. Subcellular Location: Nucleus. Tissue Specificity: Highest amounts are found in placenta, lung and heart. Similarity: Contains 2 RRM (RNA recognition motif) domains. SWISS: P29558 Gene ID: 5937 Database links: Entrez Gene: 395880 Chicken Entrez Gene: 526135 Cow Entrez Gene: 5937 Human Entrez Gene: 56878 Mouse Entrez Gene: 362138 Rat GenBank: NP_058520.1 Human Omim: 602310 Human SwissProt: Q3ZBP3 Cow SwissProt: P29558 Human SwissProt: Q91W59 Mouse SwissProt: Q5PQP1 Rat Unigene: 470412 Human Unigene: 708357 Human Unigene: 259667 Mouse Unigene: 482338 Mouse Unigene: 98522 Rat
Product Picture	Sample: Heart (Mouse) Lysate at 40 ug Heart (Mouse) Lysate at 40 ug Primary: Anti-RBMS1 (SL19776R) at 1/500 dilution Anti-RBMS1 (SL19776R) at 1/20000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 50 kD

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