Product Name	SETD3
Chinese Name	组蛋白赖氨酸N-甲基SETD3抗体
Alias	C14orf154; Chromosome 14 open reading frame 154; DKFZp761E1415; FLJ23027; Histone lysine N methyltransferase setd3; MGC87236; SET domain containing 3; SET domain containing protein 3; SETD 3; SETD3。
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, )
Applications	WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	67kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SETD3: 301-400/594
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SETD3 contains 1 SET domain. The function of the SETD3 protein remains unknown. There are 3 isoforms produced by alternative splicing. Function: Histone methyltransferase that methylates 'Lys-36' of histone H3 (H3K36me). H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation (By similarity) Subcellular Location: Nuclear Similarity: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD3 subfamily. SWISS: Q86TU7 Gene ID: 84193 Database links: Entrez Gene: 423445 Chicken Entrez Gene: 512324 Cow Entrez Gene: 490852 Dog Entrez Gene: 84193 Human Entrez Gene: 52690 Mouse Entrez Gene: 100152552 Pig Entrez Gene: 299295 Rat Entrez Gene: 705369 Rhesus monkey Entrez Gene: 549331 Xenopus tropicalis Entrez Gene: 337193 Zebrafish SwissProt: Q5ZML9 Chicken SwissProt: E2RBS6 Dog SwissProt: Q86TU7 Human SwissProt: Q91WC0 Mouse SwissProt: B7ZUF3 Xenopus tropicalis SwissProt: Q7SXS7 Zebrafish Unigene: 510407 Human
Product Picture	Sample: Lung (Mouse) Lysate at 40 ug Testis (Mouse) Lysate at 40 ug Primary: Anti-SETD3 (SL19668R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 69 kD Observed band size: 69 kD

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