Product Name	SERCA3
Chinese Name	肌浆/内质网钙ATP酶3抗体
Alias	Adenosine triphosphatase calcium; AT2A3_HUMAN; Atp2a3; ATPase Ca(2+) transporting ubiquitous; ATPase Ca++ transporting ubiquitous; Calcium pump 3; Calcium translocating P type ATPase; Sarco/endoplasmic reticulum Ca2+ ATPase; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA 3; SERCA3; SERCA3b; SR Ca(2+) ATPase 3; SR Ca(2+)-ATPase 3.
Research Area	Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Chicken, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	114kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SERCA3: 101-200/1043
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Subcellular Location: Nucleus membrane. Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane. Tissue Specificity: Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues. Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. SWISS: Q93084 Gene ID: 489 Database links: Entrez Gene: 395707 Chicken Entrez Gene: 512313 Cow Entrez Gene: 489 Human Entrez Gene: 53313 Mouse Entrez Gene: 25391 Rat Entrez Gene: 495440 Xenopus laevis Entrez Gene: 779786 Xenopus tropicalis Omim: 601929 Human SwissProt: Q9YGL9 Chicken SwissProt: Q93084 Human SwissProt: Q64518 Mouse SwissProt: P18596 Rat Unigene: 513870 Human Unigene: 6306 Mouse Unigene: 9920 Rat
Product Picture	Sample: Jurkat Cell (Human) Lysate at 40 ug RajiCell (Human) Lysate at 40 ug K562 Cell (Human) Lysate at 40 ug Primary: Anti-SERCA3(SL19653R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 114kD Observed band size: 114kD

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