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Product Name ONECUT3 Chinese Name 转录因子ONECUT3抗体 Alias OC 3; OC-3; OC3; One cut domain family member 3; One cut homeobox 3; ONEC3_HUMAN; ONECUT 3; Onecut3; Transcription factor ONECUT 3; Transcription factor ONECUT-3; Transcription factor ONECUT3. Research Area Cell biology Developmental biology transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Pig, Cow, Horse, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 50kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ONECUT3: 351-450/494 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Transcriptional activator. Binds the consensus DNA sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR.
Subcellular Location:
Nucleus.
Tissue Specificity:
Specifically expressed in brain, stomach and gut. Within the gut, expressed only in duodenum and jejunum.
Similarity:
Contains 1 CUT DNA-binding domain.
Contains 1 homeobox DNA-binding domain.
SWISS:
O60422
Gene ID:
390874
Database links:
Entrez Gene: 390874 Human
Entrez Gene: 246086 Mouse
Omim: 611294 Human
SwissProt: O60422 Human
SwissProt: Q8K557 Mouse
Unigene: 654347 Human
Unigene: 250572 Mouse
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