Product Name	PADI3 / PAD3
Chinese Name	蛋白质精氨酸亚型3抗体
Alias	HL-60 PAD; HPAD10; PAD; PAD4; PADI; PADI H protein; Padi4; PADI3_HUMAN; PADI5; PDI; PDI1; PDI2; PDI3; PDI4; PDI5; peptidyl arginine deiminase type I; peptidyl arginine deiminase type II; peptidyl arginine deiminase type III; peptidyl arginine deiminase type IV; peptidyl arginine deiminase type VI; Peptidyl arginine deiminase, type V; Peptidylarginine deiminase; Peptidylarginine deiminase IV; Peptidylarginine deiminase type VI; Protein-arginine deiminase type I; Protein-arginine deiminase type II; Protein-arginine deiminase type III; Protein-arginine deiminase type IV; Protein-arginine deiminase type-4.
Research Area	Cell biology  immunology  Signal transduction  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	75kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PADI3 / PAD3: 1-100/664
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] Function: Catalyzes the deimination of arginine residues of proteins. Subcellular Location: Cytoplasm. Tissue Specificity: Hair follicles, and epidermis at very low levels. Similarity: Belongs to the protein arginine deiminase family. SWISS: Q9ULW8 Gene ID: 51702 Database links: Entrez Gene: 51702 Human Entrez Gene: 18601 Mouse Entrez Gene: 29520 Rat Omim: 606755 Human SwissProt: Q9ULW8 Human SwissProt: Q9Z184 Mouse SwissProt: P70708 Rat Unigene: 149195 Human Unigene: 20851 Mouse Unigene: 32094 Rat
Product Picture	Sample: Pancreas (Mouse) Lysate at 40 ug Primary: Anti-PADI3 / PAD3 (SL19621R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 75 kD Observed band size: 75 kD Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-PADI3 / PAD3 (SL19621R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 75 kD Observed band size: 75 kD

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