Product Name	NT5C/dNT1
Chinese Name	胞质5'，3'核苷酸抗体
Alias	3''-pyrimidine nucleotidase; 5' nucleotidase, deoxy (pyrimidine); 5' nucleotidase, deoxy (pyrimidine), cytosolic type C; 5''(3'')-deoxyribonucleotidase; 5'(3')-deoxyribonucleotidase, cytosolic type; 5', 3'-nucleotidase, cytosolic; 5-prime,3-prime-nucleotidase, cytosolic; cdN; Cytosolic 5''; cytosolic 5',3'-pyrimidine nucleotidase; cytosolic type; cytosolic type C,5',3'-nucleotidase; cytosolic,uridine 5'-monophosphate phosphohydrolase 2; Deoxy 5' nucleotidase 1; Deoxy-5''-nucleotidase 1; Deoxyribonucleotidase, cytosolic, 1; DNT; dNT-1; dNT1; Nt5c; NT5C_HUMAN; P5N2; PN-I; PN-II; Pyrimidine 5-prime nucleotidase 2; UMPH2; uridine 5'-monophosphate phosphohydrolase 2; uridine 5-prime monophosphate hydrolase 2.
Research Area	Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	23, 13kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NT5C/dNT1: 101-201/201
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011] Function: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in skeletal muscle, heart and pancreas. Similarity: Belongs to the 5'(3')-deoxyribonucleotidase family. SWISS: Q8TCD5 Gene ID: 30833 Database links: Entrez Gene: 30833 Human Omim: 191720 Human SwissProt: Q8TCD5 Human Unigene: 67201 Human

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