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Product Name NRN1L Chinese Name 转化神经突起蛋白1样蛋白抗体 Alias MRCC2446; Neuritin-like protein; Nrn1l; NRN1L_HUMAN; UNQ2446/PRO5725. Research Area Cell biology immunology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 18kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NRN1L: 81-165/165 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail NRN1L is a 165 amino acid membrane protein that belongs to the neuritin family. The gene that encodes NRN1L consists of approximately 1,495 bases and maps to human chromosome 16q22.1. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, when mutated, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Alterations in the CREB gene and NOD2 gene, both of which are located on chromosome 16, results in Rubinstein-Taybi syndrome and Crohn's disease, respectively.
Subcellular Location:
Cell membrane.
Similarity:
Belongs to the neuritin family.
SWISS:
Q496H8
Gene ID:
123904
Database links:Entrez Gene: 123904 Human
SwissProt: Q496H8 Human
Unigene: 435464 Human
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