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Product Name NPEPL1 Chinese Name 氨肽酶样蛋白1抗体 Alias Aminopeptidase like 1; Aminopeptidase-like 1; bA261P9.2; KIAA1974; NPEPL 1; NPEPL1; PEPL1_HUMAN; Probable aminopeptidase NPEPL1. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Cow, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 55kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NPEPL1: 371-470/494 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Aminopeptidases are widely distributed in eukaryotes and prokaryotes. These enzymes catalyze the removal of amino acids from the N-termini of proteins or peptide substrates. Aminopeptidases are involved in regulating hormone levels and are essential for digestive and intracellular protein metabolism. NPEPL1, also referred to as aminopeptidase-like 1, is a 523 amino acid protein that belongs to the peptidase M17 family and is ubiquitously expressed. NPEPL1 may be involved in the processing, catabolism and degradation of intracellular proteins by catalyzing the removal of unsubstituted N-terminal amino acids from various peptides. NPEPL1 contains several zinc binding sites and and is expressed as three isoforms due to alternative splicing events.
Function:
Probably catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
Tissue Specificity:
Ubiquitously expressed.
Similarity:
Belongs to the peptidase M17 family.
SWISS:
Q9HAU8
Gene ID:
79716
Database links:Entrez Gene: 79716 Human
Entrez Gene: 228961 Mouse
Entrez Gene: 734466 Xenopus laevis
Entrez Gene: 613087 Xenopus tropicalis
Entrez Gene: 550383 Zebrafish
SwissProt: Q8NDH3 Human
SwissProt: Q6NSR8 Mouse
Unigene: 654868 Human
Unigene: 295629 Mouse
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