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Rabbit Anti-NPEPL1 antibody
Rabbit Anti-NPEPL1 antibody
Aminopeptidase like 1; Aminopeptidase-like 1; bA261P9.2; KIAA1974; NPEPL 1; NPEPL1; PEPL1_HUMAN; Probable aminopeptidase NPEPL1.
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  • NO.:SL19327R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Dog,Cow,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name NPEPL1
Chinese Name 氨肽酶样蛋白1抗体
Alias Aminopeptidase like 1; Aminopeptidase-like 1; bA261P9.2; KIAA1974; NPEPL 1; NPEPL1; PEPL1_HUMAN; Probable aminopeptidase NPEPL1.  
Research Area Cell biology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Dog, Cow, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 55kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human NPEPL1: 371-470/494 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Aminopeptidases are widely distributed in eukaryotes and prokaryotes. These enzymes catalyze the removal of amino acids from the N-termini of proteins or peptide substrates. Aminopeptidases are involved in regulating hormone levels and are essential for digestive and intracellular protein metabolism. NPEPL1, also referred to as aminopeptidase-like 1, is a 523 amino acid protein that belongs to the peptidase M17 family and is ubiquitously expressed. NPEPL1 may be involved in the processing, catabolism and degradation of intracellular proteins by catalyzing the removal of unsubstituted N-terminal amino acids from various peptides. NPEPL1 contains several zinc binding sites and and is expressed as three isoforms due to alternative splicing events.

Function:
Probably catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the peptidase M17 family.

SWISS:
Q9HAU8

Gene ID:
79716

Database links:

Entrez Gene: 79716 Human

Entrez Gene: 507384 Cow

Entrez Gene: 228961 Mouse

Entrez Gene: 100144530 Pig

Entrez Gene: 311671 Rat

Entrez Gene: 734466 Xenopus laevis

Entrez Gene: 613087 Xenopus tropicalis

Entrez Gene: 550383 Zebrafish

SwissProt: Q8NDH3 Human

SwissProt: Q6NSR8 Mouse

Unigene: 654868 Human

Unigene: 295629 Mouse



Product Picture
Sample: lung (mouse) Lysate at 40 ug
Primary: Anti-NPEPL1(SL19327R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD

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