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Product Name NEURL1B Chinese Name E3Ubiquitin连接酶蛋白NEURL1B抗体 Alias E3 ubiquitin-protein ligase NEURL1B; E3 ubiquitin-protein ligase NEURL3; hNeur2; NEU1B_HUMAN; Neur2; neuralized-2 alternative protein; neuralized-2; Neuralized-like protein 1B; Neuralized-like protein 3; NEURL1B; NEURL3. Research Area Cell biology Epigenetics Ubiquitin Immunogen Species Rabbit Clonality Polyclonal Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 59kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NEURL1B: 1-100/555 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands.
Tissue Specificity:
Highest expression in brain, prostate and small intestine. In the brain the levels are higher in fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar cortex, optic nerve and the frontal lobe.
Similarity:
Contains 2 NHR (neuralized homology repeat) domains.
Contains 1 RING-type zinc finger.
SWISS:
A8MQ27
Gene ID:
54492
Database links:Entrez Gene: 54492 Human
Entrez Gene: 240055 Mouse
SwissProt: A8MQ27 Human
SwissProt: Q0MW30 Mouse
Unigene: 91521 Human
Unigene: 133211 Mouse
Unigene: 4154 Rat
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