Product Name	TGF beta Receptor III
Chinese Name	转移生长因子β受体3抗体
Alias	Beta glycan; TGF Beta R3; Betaglycan; Betaglycan proteoglycan; BGCAN; TGF beta receptor type 3; TGF-beta receptor type 3; TGF beta receptor type III; TGF-beta receptor type III; TGFB R3; TGFBR 3; TGFBR3; TGFR 3; TGFR-3; TGFR3; Transforming Growth Factor Beta Receptor III; Transforming growth factor beta receptor III betaglycan 300kDa; TGF-βRⅢ; TGFβRⅢ; TGFβ RIII; TGF β RIII; TGF-β RIII; TGFβ-RIII; Transforming growth factor beta receptor type 3.
literatures	Specific References  (2)     |     SL1910R has been referenced in 2 publications. [IF=5.191] Chao Ye. et al. Naringin in the repair of knee cartilage injury via the TGF-β/ALK5/Smad2/3 signal transduction pathway combined with an acellular dermal matrix. J Orthop Transl. 2021 Aug;:  IHC ;  Rabbit.   PubMed:10.1016/j.jot.2021.06.004 [IF=1.785] Chao Ye. et al. Naringin and bone marrow mesenchymal stem cells repair articular cartilage defects in rabbit knees through the transforming growth factor‑β superfamily signaling pathway. Exp Ther Med. 2020 Nov;20(5):1-1  IHC ;  Rabbit.   PubMed:32952649
Research Area	Tumour  Cell biology  immunology  Neurobiology  Signal transduction  Stem cells  Apoptosis  Growth factors and hormones  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	94kDa
Cellular localization	The cell membrane Extracellular matrix Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TGFBR3: 701-850/850
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]. Function: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. Subunit: Interacts with TCTEX1D4. Subcellular Location: Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. Post-translational modifications: Extensively modified by glycosaminoglycan groups (GAG). Similarity: Contains 1 ZP domain. SWISS: Q03167 Gene ID: 7049 Database links: Entrez Gene: 7049 Human Entrez Gene: 21814 Mouse Omim: 600742 Human SwissProt: Q03167 Human SwissProt: O88393 Mouse Unigene: 482390 Human Unigene: 200775 Mous 转化生长因子β受体Ⅲ，TGFβRⅢ
Product Picture	Sample: K562 Cell (Human) Lysate at 40 ug HepG2 Cell (Human) Lysate at 40 ug Hela Cell (Human) Lysate at 40 ug Primary: Anti- TGF beta Receptor III (SL1910R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 94 kD Observed band size: 110 kD Sample: Lane 1: Mouse Placenta tissue lysates Lane 2: Mouse Testis tissue lysates Lane 3: Rat Placenta tissue lysates Lane 4: Rat Testis tissue lysates Lane 5: Human HepG2 cell lysates Lane 6: Human HeLa cell lysates Lane 7: Human A431 cell lysates Primary: Anti-TGF beta Receptor III (SL1910R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 94 kDa Observed band size: 130 kDa Independently Validated Antibody, image provided by Science Direct, badge number 029661:Formalin-fixed and paraffin embedded human kidney labeled with Anti-TGF Beta R3 Polyclonal Antibody, Unconjugated (SL1910R) at 1:250. overnight at 25C followed by conjugation to the secondary antibody and DAB staining

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