Product Name	Telomerase Binding Protein, P23
Chinese Name	端粒酶Binding proteinP23抗体
Alias	Telomerase Binding Protein，P23; Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; cPGES; Telomerase-binding protein p23; Hsp90 co-chaperone; Progesterone receptor complex p23; PTGES3; P23; TEBP; TEBP_HUMAN.
Research Area	Tumour  Cell biology  immunology  Neurobiology  Apoptosis  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	18kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Telomerase Binding Protein, P23: 31-130/160
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family. Function: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Subunit: Binds to telomerase and to the progesterone receptor. Subcellular Location: Cytoplasm. Similarity: Belongs to the p23/wos2 family. Contains 1 CS domain. SWISS: Q15185 Gene ID: 10728 Database links: Entrez Gene: 10728 Human Entrez Gene: 100043508 Mouse Entrez Gene: 100048119 Mouse Entrez Gene: 56351 Mouse Entrez Gene: 362809 Rat Omim: 607061 Human SwissProt: Q15185 Human SwissProt: Q9R0Q7 Mouse SwissProt: P83868 Rat Unigene: 50425 Human Unigene: 305816 Mouse Unigene: 2344 Rat Telomerase Binding Protein,P23是一种端粒酶Binding protein。
Product Picture	Sample: Jurkat(Human) Cell Lysate at 30 ug Primary: Anti-Telomerase Binding Protein, P23 (SL1909R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 18 kD Observed band size: 18 kD Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Telomerase Binding Protein, P23 Antibody, Unconjugated(SL1909R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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