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Product Name METRNL Chinese Name METRNL蛋白抗体 Alias Meteorin, glial cell differentiation regulator like; Meteorin-like protein; METRL_HUMAN; Metrnl. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 30kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human METRNL: 81-180/311 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail METRNL is a 311 amino acid secreted protein belonging to the Meteorin family and may have similar roles to that of the Meteorin protein. METRNL is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Subcellular Location:
Secreted.
Tissue Specificity:
Highly expressed in the skeletal muscle, in subcutaneous adipose tissue, epididymal white adipose tissue depotsand heart. Also expressed in brown adipose tissues and kidney.
Similarity:
Belongs to the meteorin family.
SWISS:
Q641Q3
Gene ID:
284207
Database links:Entrez Gene: 284207 Human
SwissProt: Q641Q3 Human
Unigene: 378821 Human
Unigene: 64557 Rat
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