Product Name	Methionine Sulfoxide Reductase A
Chinese Name	蛋氨酸亚砜还原酶MSRA抗体
Alias	Cytosolic methionine S sulfoxide reductase; cytosolic methionine-S-sulfoxide reductase; Methionine sulphoxide reductase A; Mitochondrial peptide methionine sulfoxide reductase; MSR A; MSRA; MSRA_HUMAN; peptide met (O) reductase; Peptide Met(O) reductase; Peptide methionine (S) S oxide reductase; Peptide-methionine (S)-S-oxide reductase; PMSR; Protein methionine S oxide reductase; Protein-methionine-S-oxide reductase.
Research Area	Tumour  Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	26kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Methionine Sulfoxide Reductase A: 21-120/235
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] Function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Subcellular Location: Cytoplasm; Cytoplasm. Nucleus and Mitochondrion. Tissue Specificity: Ubiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus. Similarity: Belongs to the MsrA Met sulfoxide reductase family. SWISS: Q9UJ68 Gene ID: 4482 Database links: Entrez Gene: 281312 Cow Entrez Gene: 4482 Human Entrez Gene: 110265 Mouse Entrez Gene: 29447 Rat Omim: 601250 Human SwissProt: P54149 Cow SwissProt: Q9UJ68 Human SwissProt: Q9D6Y7 Mouse SwissProt: Q923M1 Rat Unigene: 490981 Human Unigene: 26713 Mouse Unigene: 163306 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Methionine Sulfoxide Reductase A) Polyclonal Antibody, Unconjugated (SL18805R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Methionine Sulfoxide Reductase A) Polyclonal Antibody, Unconjugated (SL18805R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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