Product Name	Membrin
Chinese Name	Membrin蛋白抗体
Alias	2310032N09Rik; 27 kDa Golgi SNARE protein; Bos1; EPM6; Golgi SNAP receptor complex member 2; Golgi SNARE; Gosr2; GOSR2_HUMAN; Gs27; Membrin; SNARE.
Research Area	Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	25kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Membrin: 101-200/212
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this gene may be involved in familial essential hypertension. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. Subcellular Location: Golgi apparatus membrane. DISEASE: Epilepsy, progressive myoclonic 6 (EPM6) [MIM:614018]: A neurologic disorder characterized by onset of ataxia in the first years of life, followed by action myoclonus and seizures later in childhood, and loss of independent ambulation in the second decade. Cognition is not usually affected, although mild memory difficulties may occur in the third decade. Similarity: Belongs to the GOSR2 family. SWISS: O14653 Gene ID: 9570 Database links: Entrez Gene: 9570 Human Entrez Gene: 419973 Chicken Entrez Gene: 506198 Cow Entrez Gene: 610436 Dog Entrez Gene: 56494 Mouse Entrez Gene: 64154 Rat Omim: 604027 Human SwissProt: O14653 Human SwissProt: O35166 Mouse SwissProt: O35165 Rat Unigene: 463278 Human Unigene: 195451 Mouse Unigene: 13518 Rat

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