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Product Name MEG2 Chinese Name 蛋白酪氨酸磷酸酶MEG2抗体 Alias MEG2; PTP-MEG2; non-receptor type 9; protein tyrosine phosphatase; Protein tyrosine phosphatase MEG2; Protein-tyrosine phosphatase MEG2; PTN9_HUMAN; PTPase MEG2; Ptpn9; Tyrosine protein phosphatase non receptor type 9; Tyrosine-protein phosphatase non-receptor type 9. Research Area Cell biology Signal transduction Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, Dog, Cow, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 68kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MEG2: 301-400/593 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq, Jul 2008]
Function:
Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the protein-tyrosine phosphatase family.
Non-receptor class 3 subfamily.
Contains 1 CRAL-TRIO domain.
Contains 1 tyrosine-protein phosphatase domain.
SWISS:
P43378
Gene ID:
5780
Database links:Entrez Gene: 5780 Human
Omim: 600768 Human
SwissProt: P43378 Human
Unigene: 445775 Human
Product Picture Sample:
Raw264.7 (Mouse) Lysate at 30 ug
Primary: Anti-MEG2 (SL18751R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 68 kD
Observed band size: 68 kD
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