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Product Name MCT5 Chinese Name 单羧酸Transporter5抗体 Alias MCT 5; MCT 6; MCT6; Monocarboxylate transporter 5; Monocarboxylate transporter 6; Monocarboxylic acid transporter 5; Monocarboxylic acid transporter 6; MOT6_HUMAN; SLC16A5; Solute carrier family 16 (monocarboxylic acid transporters) member 5; Solute carrier family 16 member 5. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 55kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MCT5: 1-100/487 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Function:
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Highly expressed in kidney.
Similarity:
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
SWISS:
O15374
Gene ID:
9121
Database links:Entrez Gene: 9121 Human
Omim: 603879 Human
SwissProt: O15374 Human
SwissProt: O15375 Human
Unigene: 592095 Human
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