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Rabbit Anti-MCT5 antibody
Rabbit Anti-MCT5 antibody
MCT 5; MCT 6; MCT6; Monocarboxylate transporter 5; Monocarboxylate transporter 6; Monocarboxylic acid transporter 5; Monocarboxylic acid transporter 6; MOT6_HUMAN; SLC16A5; Solute carrier family 16 (monocarboxylic acid transporters) member 5; Solute carri
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  • NO.:SL18736R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:WB
    concentration:1mg/ml
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Details

Product Name MCT5
Chinese Name 单羧酸Transporter5抗体
Alias MCT 5; MCT 6; MCT6; Monocarboxylate transporter 5; Monocarboxylate transporter 6; Monocarboxylic acid transporter 5; Monocarboxylic acid transporter 6; MOT6_HUMAN; SLC16A5; Solute carrier family 16 (monocarboxylic acid transporters) member 5; Solute carrier family 16 member 5.  
Research Area Cell biology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 55kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MCT5: 1-100/487 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Function:
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highly expressed in kidney.

Similarity:
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

SWISS:
O15374

Gene ID:
9121

Database links:

Entrez Gene: 9121 Human

Omim: 603879 Human

SwissProt: O15374 Human

SwissProt: O15375 Human

Unigene: 592095 Human



Product Picture
Sample:
Skeletal muscle(Mouse) Cell Lysate at 40 ug
Primary: Anti-MCT5 (SL18736R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55kD
Observed band size: 55 kD

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