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Product Name MAST4 Chinese Name 微管相关丝氨酸/苏氨酸激酶4抗体 Alias EC 2.7.11.1; KIAA0561; MAST 3; MAST3; MAST3_HUMAN; Microtubule associated serine/threonine protein kinase 3; Microtubule-associated serine/threonine-protein kinase 3. Research Area Cell biology Signal transduction Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Chimpanzee, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 284kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MAST4: 101-200/2626 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the microtubule-associated serine/threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Highly expressed in most normal human tissues, with an exception of in testis, small intestine, colon and peripheral blood leukocyte.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the protein kinase superfamily.
AGC Ser/Thr protein kinase family.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 PDZ (DHR) domain.
Contains 1 protein kinase domain.
SWISS:
O15021
Gene ID:
375449
Database links:Entrez Gene: 461838 Chimpanzee
Entrez Gene: 742730 Chimpanzee
Entrez Gene: 375449 Human
SwissProt: O15021 Human
Unigene: 595458 Human
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