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Product Name MAN1C1 Chinese Name MAN1C1蛋白抗体 Alias 1 2 alpha mannosidase IC; Alpha 1 2 mannosidase IC; HMIC; MAN1A3; MAN1C; Mannosidase alpha class 1C member 1; Mannosyl oligosaccharide 1 2 alpha mannosidase IC; pp6318; Processing alpha 1 2 mannosidase IC. Research Area Tumour Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 71kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MAN1C1: 151-250/630 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail MAN1C1 belongs to the glycosyl hydrolase 47 family. It is involved in the maturation of Asn-linked oligosaccharides. It trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. MAN1C1 is expressed in most tissues with the exception of lung, muscle and pancreas. It is highly expressed in placenta.
Function:
Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce first Man8GlcNAc2 then Man6GlcNAc and a small amount of Man5GlcNAc.
Tissue Specificity:
Expressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta.
Similarity:
Golgi apparatus membrane; Single-pass type II membrane protein.
SWISS:
Q9NR34
Gene ID:
57134
Database links:Entrez Gene: 57134 Human
SwissProt: Q9NR34 Human
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