Product Name	IL20
Chinese Name	白细胞介素-20抗体
Alias	Interleukin-20; four alpha helix cytokine; IL10D; Interleukin 20; Interleukin-20; ZCYTO10; IL20_MOUSE; Cytokine Zcyto10; IL-20; IL20_HUMAN; MGC96907; UNQ852/PRO1801.
Research Area	immunology  glycoprotein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	17kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse IL-20: 51-150/176
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. Function: Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3. Subcellular Location: Secreted. Tissue Specificity: Expressed at very low levels in skin, trachea, and other tissues. Similarity: Belongs to the IL-10 family. SWISS: Q9JKV9 Gene ID: 58181 Database links: Entrez Gene: 50604 Human Entrez Gene: 58181 Mouse SwissProt: Q9NYY1 Human SwissProt: Q9JKV9 Mouse 白介素20是新发现的cell factor，属于白介素10家族成员。它可由活化的外周血单一核细胞和角质形成细胞产生。与其他白介素10家族成员的受体亚单位有React Species，多用于银屑病及风湿病的研究。
Product Picture	Paraformaldehyde-fixed, paraffin embedded (rat skin tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-20) Polyclonal Antibody, Unconjugated (SL1834R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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