Product Name	LMOD1
Chinese Name	甲状腺相关眼病自身抗原抗体
Alias	1D; 64 kDa autoantigen 1D; 64 kDa autoantigen 1D3; 64 kDa autoantigen D1; 9530015K06Rik; D1; Leiomodin; Leiomodin-1; Lmod1; LMOD1_HUMAN; muscle form; SM LMOD; SM-Lmod; SMLMOD; Smooth muscle leiomodin; Thyroid associated ophthalmopathy autoantigen; Thyroid-associated ophthalmopathy autoantigen.
Research Area	Cell biology  Neurobiology  Signal transduction  Cell type markers  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Cat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	67kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LMOD1: 251-350/600
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008] Subcellular Location: Cytoplasm. Cytoplasm; cytoskeleton. Tissue Specificity: Smooth muscle (heart, skeletal muscle, colon and small intestine), a subset of striated muscle fibers, and at low level in thyroid. Similarity: Belongs to the tropomodulin family. Contains 1 WH2 domain. SWISS: P29536 Gene ID: 25802 Database links: Entrez Gene: 25802 Human Entrez Gene: 428540 Chicken Entrez Gene: 532090 Cow Entrez Gene: 100052019 Horse Entrez Gene: 93689 Mouse Entrez Gene: 304816 Rat Omim: 602715 Human SwissProt: P29536 Human SwissProt: Q8BVA4 Mouse Unigene: 519075 Human Unigene: 180124 Mouse Unigene: 66554 Rat

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