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Rabbit Anti-LINGO2 antibody
Rabbit Anti-LINGO2 antibody
LERN3; Leucine rich repeat and Ig domain containing 2; Leucine rich repeat neuronal 6C; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine-rich repeat neuronal protein 3; Leucine-rich repeat neuronal
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  • NO.:SL18284R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Zebrafish,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
  • Goods click count:23
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Details

Product Name LINGO2
Chinese Name 富含亮氨酸重复跨膜神经元2抗体
Alias LERN3; Leucine rich repeat and Ig domain containing 2; Leucine rich repeat neuronal 6C; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine-rich repeat neuronal protein 3; Leucine-rich repeat neuronal protein 6C; LIGO2_HUMAN; LINGO2; LRRN6C.  
Research Area Cell biology  Neurobiology  Transmembrane protein  The cell membrane蛋白  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Zebrafish, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 65kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human LINGO2: 331-430/606 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Lingo-2 (leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2), also known as LERN3 (leucine-rich repeat neuronal protein 3) or LRRN6C, is a 606 amino acid single-pass type I membrane protein. Lingo-2 contains 1 immunoglobulin-like C2-type domain and 13 leucine-rich repeats. Lingo-2 is a member of the LRR gene family and has been linked to essential tremor and Parkinson’s disease. Lingo-2 has a high degree of homology (61%) with Lingo-1, a regulator of neuronal death, and the expression of Lingo-2 seems to be restricted to neuronal tissue.

Subcellular Location:
Membrane.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 12 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
Q7L985

Gene ID:
158038

Database links:

Entrez Gene: 158038 Human

Entrez Gene: 242384 Mouse

Omim: 609793 Human

SwissProt: Q7L985 Human

SwissProt: Q3URE9 Mouse

Unigene: 726303 Human

Unigene: 745029 Human

Unigene: 132507 Mouse



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