Product Name	LCLAT1
Chinese Name	心磷脂酰基转移酶1抗体
Alias	1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGP acyltransferase 8; 1-AGPAT 8; 1AGPAT8; Acyl-CoA:lysocardiolipin acyltransferase 1; AGPAT8; ALCAT1; HSRG1849; lclat1; LCLT1_HUMAN; LYCAT; Lysocardiolipin acyltransferase 1; UNQ1849; UNQ1849/PRO3579.
literatures	Specific References  (1)     |     SL18190R has been referenced in 1 publications. [IF=3.115] Huiyuan Gong. et al. Upregulation of LPGAT1 Enhances Lung Adenocarcinoma Proliferation. FRONT BIOSCI-LANDMRK. 2023 May;28(5):89  WB ;  Human.   PubMed:37258473
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	49kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LCLAT1: 261-360/414
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Expressed at higher level in heart, kidney and pancreas than in brain, spleen, liver, lung, small intestine and placenta. Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. SWISS: Q6UWP7 Gene ID: 253558 Database links: Entrez Gene: 253558 Human Entrez Gene: 225010 Mouse Entrez Gene: 100217396 Pig Omim: 614241 Human SwissProt: Q6UWP7 Human SwissProt: Q3UN02 Mouse Unigene: 468048 Human Unigene: 662770 Human Unigene: 329194 Mouse
Product Picture	Sample: Liver(Mouse)Lysate at 40 ug Kidney (Mouse)Lysate at 40 ug Primary: Anti-LCLAT1(SL18190R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 49kD Observed band size: 49kD Sample:Heart (Mouse)Lysate at 40 ug Primary: Anti-LCLAT1(SL18190R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 49kD Observed band size: 49kD Sample: Heart (Mouse) Lysate at 40 ug Heart (Rat) Lysate at 40 ug Primary: Anti-LCLAT1 (SL18190R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD

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