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Product Name TOB2 Chinese Name HER2受体转换蛋白2抗体 Alias KIAA1663; Protein Tob2; Protein Tob4; Tob2; TOB2_HUMAN; TOB4; Transducer of erbB 2 2; Transducer of erbB-2 2; Transducer of ERBB2, 2; TROB2. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 37kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TOB2: 151-250/344 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail TOB2 belongs to the TOB (see TOB1; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.[supplied by OMIM, Apr 2004]
Function:
Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the BTG family.
SWISS:
Q14106
Gene ID:
10766
Database links:Entrez Gene: 10766 Human
Entrez Gene: 100735653 Guinea pig
Entrez Gene: 100055713 Horse
Entrez Gene: 57259 Mouse
Entrez Gene: 100620046 Sheep
Omim: 607396 Human
SwissProt: Q14106 Human
SwissProt: Q9JM55 Mouse
Unigene: 474978 Human
Unigene: 323595 Mouse
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